POST FEVER RETINITIS AND SINGLE WONDER DRUG FOR ITS VARIOUS ETIOLOGIES

Main Article Content

Vikas Sharma Raji K Sankalp Seth Yogesh Yadav Gaurav Kapoor

Abstract

Introduction: Post-fever retinitis is an infectious or para-infectious entity which involve retinal layer of the eye and has variable clinical manifestations. Post-fever retinitis has varied etiologies, namely bacteria or viral.


Case Report: We present a series of four cases of post fever retinitis with common history of flu-like illness followed by blurring of vision, all four patients had different clinical picture, they were investigated thoroughly to ascertain etiological agents and were treated with oral Doxycycline. All cases had an excellent visual recovery by the end of the treatment with complete resolution of clinical signs.


Discussion: It is difficult to pin-point the exact etiology of PFR just on the basis of clinical presentation and hence, proper history, clinical examination, serological investigations and awareness of ongoing epidemics may help to identify the etiological organism.


Conclusion: Post fever retinitis is an easy diagnosis based on antecedent history of flu like illness and typical fundus findings. Oral doxycycline is a safe and wonderful drug for PFR cases.

Keywords

Post fever retinitis, Flu Like illness, Subretinal fluid, Doxycycline, Steroids

Article Details

How to Cite
SHARMA, Vikas et al. POST FEVER RETINITIS AND SINGLE WONDER DRUG FOR ITS VARIOUS ETIOLOGIES. International Journal of Retina, [S.l.], v. 6, n. 2, p. 153, sep. 2023. ISSN 2614-8536. Available at: <https://ijretina.com/index.php/ijretina/article/view/219>. Date accessed: 06 oct. 2024. doi: https://doi.org/10.35479/ijretina.2023.vol006.iss002.219.
Section
Case Report

References

1. Kawali A, Mahendradas P, Mohan A, et al. Epidemic retinitis. Ocular Immunol Inflam 2019; 27: 571–577.
2. Vishwanath S, Badami K, Sriprakash KS, et al. Post-fever retinitis: a single center experience from south India. Int Ophthalmol 2014; 34: 851–857.
3. Mahendradas P, Kawali A, Luthra S, et al. Post-fever retinitis–newer concepts. Indian J Ophthalmol 2020; 68: 1775–1786.
4. Sundar M D, Chawla R, Balaji A, Garg I, Kalathil R, Hasan N, Vikas SJ, Kumar A. Clinical features, optical coherence tomography findings and treatment outcomes of post-fever retinitis. Ther Adv Ophthalmol. 2020 Dec 18;12:2515841420979111. doi: 10.1177/2515841420979111. PMID: 33415316; PMCID: PMC7750750.
5. Dreyer RF, Hopen G, Gass JD, et al. Leber’s idiopathic stellate neuroretinitis. Arch Ophthalmol 1984; 102: 1140–1145.
6. Purvin V, Sundaram S and Kawasaki A. Neuroretinitis: review of the literature and new observations. J Neuroophthalmol 2011; 31: 58–68.
7. Abdelhakim A and Rasool N. Neuroretinitis: a review. Curr Opinion Ophthalmol 2018; 29: 514–519.
8. Karkhur S, Soni D. Clinical spectrum, disease course and management outcome of post-fever retinitis cases: experience from a tertiary eye institute in central India. Int Ophthalmol. 2022 Sep;42(9):2697-2709. doi: 10.1007/s10792-022-02258-w. Epub 2022 Apr 7. PMID: 35391586; PMCID: PMC8989109.
9. Chawla R, Pundlik GA, Chaudhry R, et al. Rickettsial retinitis: direct bacterial infection or an immune-mediated response? Indian J Ophthalmol 2017; 65: 1038–1041.
10. Kawali A, Mahendradas P, Srinivasan P, et al. Rickettsial retinitis—an Indian perspective. J Ophthalmic Inflamm Infect 2015; 5: 37.
11. Kawali A, Srinivasan S, Mohan A, et al. Epidemic retinitis with macular edema–treatment outcome with and without steroids. Ocular Immunol Inflam. Epub ahead of print 21 January 2020. DOI: 10.1080/09273948.2019.1704792.
12. Smilack JD. The tetracyclines. Mayo Clin Proc 1999; 74: 727–729.
13. Rothan HA, Mohamed Z, Paydar M, et al. Inhibitory effect of doxycycline against dengue virus replication in vitro. Arch Virol 2014; 159: 711–718.
14. Rothan HA, Bahrani H, Mohamed Z, et al. A combination of doxycycline and ribavirin alleviated chikungunya infection. PLoS ONE 2015; 10: e0126360.
15. ChawlaR,PundlikGA,ChaudhryR,ThakurC.Rickettsialretinitis: Direct bacterial infection or an immune-mediated response? Indian J Ophthalmol 2017;65:1038-41.
16. AyachitA,AyachitG,JoshiS,SameeraVV.Commentary:Rickettsial retinitis - Direct bacterial infection or an immune-mediated response? Indian J Ophthalmol 2017;65:1041-3.