A CURIOUS CASE OF CENTRAL RETINAL VEIN OCCLUSION IN A YOUNG PATIENT FOLLOWING DENGUE FEVER

Main Article Content

Anuradha Singh Vikas Sharma Shailesh Mogra

Abstract

 Introduction: Central retinal vein occlusion (CRVO) is a common ocular disease which can be responsible for significant ocular morbidity in the adult population. It is most commonly associated with lifestyle diseases especially hypertension in older age groups, but may have a variety of etiologies including genetically inherited disorders.


Case report: A 27-year-old female patient presented to our out patient department (OPD) with history of diminished vision in left eye of 03 days duration. The patient gave history of contracting dengue fever three weeks prior to the onset of symptoms. On evaluation she was found to have CRVO of the left eye with no macular edema. The patient was investigated for other causes of CRVO and was found to have mildly reduced serum homocysteine and deranged serum iron studies. The patient was managed conservatively with good visual recovery and is presently on follow up for early detection of complications for CRVO.


Discussion: The patient presented with multiple etiologies of CRVO, however, each was subclinical in nature. Conservative management for ocular symptoms along with treatment of systemic deficiencies by the physician lead to good visual outcome and generalized well being of the patient.


Conclusion: CRVO is being increasingly seen in the younger age group. Multiple etiologies may need to be ruled out, along with lifestyle diseases which are on an incline in the younger population. Close follow up with treatment is required to detect complications early, and provide a good visual outcome. To our knowledge, this is the third reported case of CRVO related to dengue fever.

Keywords

CRVO, dengue, homocysteine, carotid doppler

Article Details

How to Cite
SINGH, Anuradha; SHARMA, Vikas; MOGRA, Shailesh. A CURIOUS CASE OF CENTRAL RETINAL VEIN OCCLUSION IN A YOUNG PATIENT FOLLOWING DENGUE FEVER. International Journal of Retina, [S.l.], v. 7, n. 1, p. 62, feb. 2024. ISSN 2614-8536. Available at: <https://ijretina.com/index.php/ijretina/article/view/272>. Date accessed: 28 sep. 2024. doi: https://doi.org/10.35479/ijretina.2024.vol007.iss001.272.
Section
Case Report

References

1.Wittström E. Central Retinal Vein Occlusion in Younger Swedish Adults: Case Reports and Review of the Literature. Open Ophthalmol J. 2017 May 22;11:89-102. doi: 10.2174/1874364101711010089. PMID: 28603574; PMCID: PMC5447937.
2.Zhang XT, Zhong YF, Xue YQ, Li SQ, Wang BY, Zhang GQ, Hidasa I, Zhang H. Clinical Features of Central Retinal Vein Occlusion in Young Patients. Ophthalmol Ther. 2022 Aug;11(4):1409-1422. doi: 10.1007/s40123-022-00534-7. Epub 2022 Jun 13. PMID: 35697973; PMCID: PMC9191544.
3.Lindsell LB, Lai MM, Fine HF. Current concepts in managing retinal vein occlusion in young patients. Ophthalmic Surg Lasers Imaging Retina. 2015 Jul-Aug;46(7):695-701. doi: 10.3928/23258160-20150730-02. PMID: 26271084.
4.Terao R, Fujino R, Ahmed T. Risk Factors and Treatment Strategy for Retinal Vascular Occlusive Diseases. J Clin Med. 2022 Oct 27;11(21):6340. doi: 10.3390/jcm11216340. PMID: 36362567; PMCID: PMC9656338.
5.Tauqeer Z, Bracha P, McGeehan B, VanderBeek BL. Hypercoagulability Testing and Hypercoagulable Disorders in Young Central Retinal Vein Occlusion Patients. Ophthalmol Retina. 2022 Jan;6(1):37-42. doi: 10.1016/j.oret.2021.03.009. Epub 2021 Mar 24. PMID: 33774219; PMCID: PMC8460678.
6.Yang V, Turner LD, Imrie F. Central retinal vein occlusion secondary to severe iron-deficiency anaemia resulting from a plant-based diet and menorrhagia: a case presentation. BMC Ophthalmol. 2020 Mar 19;20(1):112. doi: 10.1186/s12886-020-01372-6. PMID: 32192459; PMCID: PMC7081704.
7.Zuche M, Ladewig MS. Kombinierter Netzhautgefäßverschluss nach sportlicher Überanstrengung im jungen Alter : Ein ungewöhnlicher Fall als interdisziplinäre Herausforderung [Combined retinal vascular occlusion after overexertion in sport at a young age : An unusual case as interdisciplinary challenge]. Ophthalmologe. 2021 Sep;118(9):944-947. German. doi: 10.1007/s00347-020-01222-2. Epub 2020 Sep 15. PMID: 32930866.
8.Sedlak L, Świerczyńska M, Pojda-Wilczek D. Combined central retinal vein and cilioretinal artery occlusion in a 25-year-old woman. Rom J Ophthalmol. 2022 Apr-Jun;66(2):178-184. doi: 10.22336/rjo.2022.35. PMID: 35935085; PMCID: PMC9289772.
9.Rehak M, Wiedemann P. Retinal vein thrombosis: pathogenesis and management. J Thromb Haemost. 2010 Sep;8(9):1886-94. doi: 10.1111/j.1538-7836.2010.03909.x. PMID: 20492457.
10.Ahluwalia J, Rao S, Varma S, Gupta A, Bose S, Masih J, Das R, Kumar N, Naseem S, Sharma P, Sachdeva MU, Varma N. Thrombophilic risk factors are uncommon in young patients with retinal vein occlusion. Retina. 2015 Apr;35(4):715-9. doi: 10.1097/IAE.0000000000000366. PMID: 25299970.
11.Kanungo S, Shukla D, Kim R. Branch retinal artery occlusion secondary to dengue fever. Indian J Ophthalmol. 2008 Jan-Feb;56(1):73-4. doi: 10.4103/0301-4738.37606. PMID: 18158412; PMCID: PMC2636058.
12.Pisit Preechawat, Anuchit Poonyathalang, Sireedhorn Kurathong, Kitikul Leelawongs & VirojPongthanapisit (2012) Non-ischaemic Central Retinal Vein Occlusion after Dengue Viral Infection, Neuro-Ophthalmology, 36:1, 26-28, DOI: 10.3109/01658107.2011.643332.
13.Velaitham P, Vijayasingham N. Central retinal vein occlusion concomitant with dengue fever. Int J Retina Vitreous. 2016 Jan 20;2:1. doi: 10.1186/s40942-016-0027-x. PMID: 27847619; PMCID: PMC5088483.